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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $71 | 5 days |
Description | Pomalidomide-PEG6-butyl iodide is a chemically synthesized E3 ligase ligand-linker conjugate, combining the cereblon ligand from Pomalidomide with a 6-unit PEG linker, commonly used in PROTAC technology [1]. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one ligand binds to an E3 ubiquitin ligase, while the other targets the protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 761.6 |
Formula | C31H44IN3O11 |
Cas No. | 1835705-74-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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